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Description
Trex overhaul to be compatible with Seurat v5 and move away from reticulate. Similar to Ibex overhaul for the submission to Bioconductor.
Proposed Changes
- Integration of Ibex with immApex
- Move towards zenodo hosting of models
- Updated Seurat object to v5
- Dedicated basilisk environment
- Update support for SCE format for
runTrex() - Update
CoNGAfy()to function with all versions of Seurat - Update
quietTCRgenes()to useVariableFeatures()call for SeuratV5 and backward compatibility. - Update
annotateDB()(per issue- Automate Library Pull
- Add better support for HLA information/Add to meta data [see issue]
- Expand matching system beyond edit distance
After these changes the plan will be to submit to bioconductor similar to the recently accepted Ibex.
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