It would be nice to be able to substitute values in like v = 23 m/s, and have the math system understand how to apply SI prefix changes (eg convert to 0.023 km/s upon request).
Additionally, when you take a distance in (meters) and divide it by a duration (in seconds), the math system would understand that the new quantity is in m/s.
Wolfram Alpha does a really good job of this feature, and it's a killer feature to be able to have the math system do the unit analysis/cancellation alongside the math.