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polyester/R/simulate_experiment.R
Lines 135 to 149 in 29263d1
| #' @param fold_changes Matrix specifying multiplicative fold changes | |
| #' between groups. There is no default, so you must provide this argument. | |
| #' In real data sets, lowly-expressed transcripts often show high fold | |
| #' changes between groups, so this can be kept in mind when setting | |
| #' \code{fold_changes} and \code{reads_per_transcript}. This argument must | |
| #' have the same number of columns as there are groups as | |
| #' specified by \code{num_reps}, and must have the same number of rows as | |
| #' there are transcripts in \code{fasta}. A fold change of X in matrix entry | |
| #' i,j means that for replicate j, the baseline mean number of reads | |
| #' (reads_per_transcript[i]) will be multiplied by X. Note that the | |
| #' multiplication happens before the negative binomial value | |
| #' (for the number of reads that *actually will* be | |
| #' drawn from transcript i, for replicate j) is drawn. This argument is | |
| #' ignored if \code{length(num_reps)} is 1 (meaning you only have 1 group in | |
| #' your simulation). |
A fold change of X in matrix entry i,j means that for replicate j, the baseline mean number of reads (reads_per_transcript[i]) will be multiplied by X.
should probably be
A fold change of X in matrix entry i,j means that for group j, the baseline mean number of reads (reads_per_transcript[i]) will be multiplied by X.
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