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Can Allo be used for transcriptome expression calculation in polyploid genome (haplotype-resolved)? #6

@yt619

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@yt619

Hi -

Is this software capable of quantifying gene expression in homoeologous polyploids? Given that there are numerous repetitive regions between homoeologous chromosomes, if a haplotype-assembled genome is used as the reference genome, can Allo be used to quantify the expression levels of each gene? Although the challenge of mapping highly homologous regions exists, this should still provide a viable method for expression quantification?

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