There have been many tools for joint dimensionality reduction (JDR) of multi-omics data, many of which have been benchmarked1, however the suitability of various tools seems to be largely dependent on the data and the downstream analysis being performed.
Here we present MARMOT (Model Analysis and compaRison for Multi-Omics Tools), an R tool for comparing JDR models in different conditions or with different inputs.
MARMOT is available as a GitHub package and can be installed using devtools.
install.packages("devtools") # if not already installed
library(devtools)
install_github("kuijjerlab/MARMOT")
- Cantini, L., Zakeri, P., Hernandez, C. et al. Benchmarking joint multi-omics dimensionality reduction approaches for the study of cancer. Nat Commun 12, 124 (2021). https://doi.org/10.1038/s41467-020-20430-7
