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Open source lateral flow strip reader

This repo is made for our open-source lateral flow strip reader project. The project was originally created for our paper titled Development of Automated Detection and Wireless Reporting for a Handheld Point-of-Care Test. In the paper you can find a detailed performance analysis of the original hardware. To build the device you will need in-depth knowledge of electronics, as well as a decent FDM 3D printer such as the Original Prusa i3 MK3S.

  • Optical readout module built on an ESP12F (ESP8266) Wi-Fi MCU and a PIC12F675 microcontroller, driving focused red LEDs and wide-area photodiodes to distinguish test/control lines with high sensitivity.
  • Battery-powered design using two AAA cells and a single switching regulator for stable 3.3 V operation, with power-saving multiplexed LED activation and ADC sampling.
  • Wireless data transmission over a secure WPA2 ad-hoc Wi-Fi network, sending raw intensity readings to a MATLAB application for real-time display, analysis and export to Excel.
  • 3D-printed cartridge interface, aligning two lateral flow strips under an enclosure to block ambient light and ensure reproducible measurements.

Contents

  • hardware/ – PCB schematics and BOM for ESP12F + PIC readout board
  • firmware/ – Source for ESP8266 and PIC12F675 (LED control, ADC, UART)
  • software/ – MATLAB GUI application for data acquisition and export
  • docs/ – Dataset and reference publication (BEC2020_TP_MF_CB_TR.pdf)

Quick Start

  1. Assemble PCB and load firmware.
  2. Insert batteries and power on—the module creates a Wi-Fi network LFStripReader.
  3. Connect PC, launch MATLAB app, and pipette sample to cartridge.
  4. View live readings and save results automatically.

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Open-source lateral flow strip reader

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